Daniel Martinez Molina has spent the last 13 years working with the development and applications of the Cellular Thermal Shift Assay (CETSA). In 2013, after publishing the first proof of concept study, Daniel and friends founded the company Pelago Bioscience, a contract research organization with the aim to accelerate the use of CETSA in drug discovery. Daniel is still today the CSO of Pelago Bioscience where he is responsible for the development of the assay for commercial purposes.
Before CETSA became Daniel’s favourite speaking subject he had just defended his thesis after a PhD program at Karolinska Institutet and Stockholm University. The thesis subject was the development of methods for optimizing membrane protein expression and stability for structural investigations using X-ray crystallography. In 2007 he also solved the first high resolution structure of a human membrane protein (Leukotriene C4 Synthase).